VARIATION AMONG MOUSE STRAINS IN RESPONSIVENESS TO MIGRATION-INHIBITORY FACTOR

被引：15

作者：

TAGLIABUE, A

HERBERMAN, RB

MCCOY, JL

机构：

[1] Laboratory of Immunodiagnosis, National Cancer Institute, National Institutes of Health, Bethesda

来源：

CELLULAR IMMUNOLOGY | 1979年 / 45卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0008-8749(79)90407-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Mineral oil-induced peritoneal exudate cells (PEC) from 10 different inbred mouse strains were tested for their responses to macrophage migration inhibitory factor (MIF). PEC from 5 out of 10 mouse strains responded to MIF, PEC from BALB/c mice showed an intermediate responsiveness, and PEC from A/J, C3H/HeJ, CBA/N, and C57BL/10ScCR mice were refractory to MIF. MIF responsiveness was not linked to the H-2 complex. However, a possible link between responsiveness to LPS and MIF was suggested, since the mouse strains not responding to MIF were previously reported to be deficient for responses to LPS. © 1979.

引用

页码：464 / 468

页数：5