Hand bone mass in rheumatoid arthritis: A review of the literature

被引:11
作者
Kilic, Gamze [1 ]
Ozgocmen, Salih [1 ]
机构
[1] Erciyes Univ, Div Rheumatol, Dept Phys Med & Rehabil, Sch Med,Gevher Nesibe Hosp, Talas Yolu Uzeri, TR-38039 Kayseri, Turkey
关键词
Rheumatoid arthritis; Hand bone density; Dual X-ray absorptiometry; Periarticular; Osteoporosis;
D O I
10.5312/wjo.v6.i1.106
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Rheumatoid arthritis (RA) is a common chronic inflammatory disease and periarticular osteoporosis or osteopenia of the inflamed hand joints is an early feature of RA. Quantitative measurement of hand bone loss may be an outcome measure for the detection of joint destruction and disease progression in early RA. This systematic review examines the published literature reporting hand bone mass in patients with RA, particularly those using the dual X-ray absorptiometry (DXA) methods. The majority of the studies reported that hand bone loss is associated with disease activity, functional status and radiological progression in early RA. Quantitative measurement of hand bone mineral density by DXA may be a useful and practical outcome measure in RA and may be predictive for radiographic progression or functional status in patients with early RA.
引用
收藏
页码:106 / 116
页数:11
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