PHARMACOLOGIC EFFECTS OF TETRODOTOXIN - CARDIOVASCULAR AND ANTIARRHYTHMIC ACTIVITIES

被引：8
作者：
BERNSTEIN, ME
机构：
[1] Laboratory of Neurological Research, Los Angeles County-University, Southern California Medical Center, Los Angeles, CA
来源：
TOXICON | 1969年 / 7卷 / 04期
关键词：
D O I：
10.1016/0041-0101(69)90029-4
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
The effects of tetrodotoxin (TTX) on various biologic parameters have been investigated. Drug interaction studies have demonstrated that TTX can prevent or reverse ouabain-induced bradycardia, tachycardia, and arrhythmias. Reserpine has been shown to completely block the actions of this toxin. Propranolol and phenoxybenzamine tended to modify various actions of TTX. Species differences have been noted. The implications of these results are discussed. © 1969.
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页码：287 / +
页数：1
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