SYNTHESIS OF PROTECTED 3-METHYLASPARTIC ACIDS FROM GLUTAMIC ANHYDRIDE VIA NICKELACYCLES

被引：16
作者：
CASTANO, AM
ECHAVARREN, AM
机构：
[1] CSIC,INST QUIM ORGAN,JUAN CIERVA 3,E-28006 MADRID,SPAIN
[2] UNIV AUTONOMA MADRID,DEPT QUIM,E-28049 MADRID,SPAIN
来源：
TETRAHEDRON LETTERS | 1993年 / 34卷 / 27期
关键词：
D O I：
10.1016/S0040-4039(00)79352-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of fully protected beta-methyl aspartic acids from (+/-)-glutamic anhydride has been achieved by means of ring contraction of the derived nickelacycle followed by insertion of an isocyanide. The intermediate five-membered ring nickelacycles were isolated and characterized spectroscopically.
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页码：4361 / 4362
页数：2
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