CHANGES IN IMMUNOLOGICAL RESPONSE IN TONSILLECTOMIZED CHILDREN .2. DECREASED CELLULAR-RESPONSE

被引：14

作者：

MORENO, PM

SANCHEZ, M

SAINZ, M

GUTIERREZ, F

机构：

[1] Servicio de fnmunologia, Hospital Universitario de Granada

来源：

CLINICAL OTOLARYNGOLOGY | 1992年 / 17卷 / 05期

关键词：

TONSIL; TONSILLITIS; IMMUNOLOGY; CELLULAR RESPONSE;

D O I：

10.1111/j.1365-2273.1992.tb01678.x

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

The immunological cellular response was studied in 22 children aged between 5 and 10 years. One week before and one month after tonsillectomy, the mitogenic response to phytohaemagglutinin (PHA), concanavalin (ConA) and pokeweed mitogen (PWM) was tested. Our results showed statistically significant decreases in stimulation index (SI) to PHA, ConA and PWM after tonsillectomy. This suggests that the tonsils may influence the cellular immune status in children. The higher level of preoperative activity in children with recurrent tonsillitis could be understood as the result of stimulation of lymphocytes by bacteria.

引用

页码：380 / 382

页数：3

共 13 条

[1] AMLOT PL, 1976, CLIN EXP IMMUNOL, V26, P520
[2] COMPARISON OF THE MICROBIOLOGY OF RECURRENT TONSILLITIS BETWEEN CHILDREN AND ADULTS
BROOK, I
FOOTE, PA
[J]. LARYNGOSCOPE, 1986, 96 (12) : 1385 - 1388
[3] DEDIO RM, 1988, ARCH OTOLARYNGOL, V114, P763
[4] DIXON WJ, 1983, BMDP STATISTICAL SOF
[5] FIGUEREDO MA, 1979, CLIN EXP IMMUNOL, V37, P140
[6] FOX RI, 1981, J IMMUNOL, V126, P2062
[7] FREID A, 1982, ACTA OTO-LARYNGOL, V386, P127
[8] SUB-POPULATIONS OF HUMAN LYMPHOCYTE-T .7. CELLULAR BASIS OF CONCANAVALIN A-INDUCED T-CELL-MEDIATED SUPPRESSION OF IMMUNOGLOBULIN PRODUCTION BY LYMPHOCYTE-B FROM NORMAL HUMANS
GUPTA, S
SCHWARTZ, SA
GOOD, RA
[J]. CELLULAR IMMUNOLOGY, 1979, 44 (02) : 242 - 251
[9] MCKENZIE IFC, 1979, ADV IMMUNOL, V27, P180
[10] NAKAMURA RM, 1982, IMMUNOLOGIC ANAL REC, P96

← 1 2 →