URINARY INHIBITORS OF THE FORMATION OF CALCIUM-OXALATE

被引：16
作者：
SUTOR, DJ [1 ]
PERCIVAL, JM [1 ]
DOONAN, S [1 ]
机构：
[1] UNIV LONDON UNIV COLL,DEPT CHEM,LONDON WC1E 6BT,ENGLAND
来源：
BRITISH JOURNAL OF UROLOGY | 1979年 / 51卷 / 04期
关键词：
D O I：
10.1111/j.1464-410X.1979.tb04703.x
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
Summary— Normal urine was examined for substances which inhibited the formation of calcium oxalate, using a separation scheme which involved ultrafiltration, alcohol precipitation, electrophoresis and paper chromatography. The major anionic inhibitors were found to be citric acid, isocitric acid and pyrophosphate. The inhibitory activity of urine and that of an artificial urine having the same concentration of urea, creatinine, sodium, potassium, magnesium, calcium, ammonia, sulphate, chloride, inorganic phosphate, oxalate, citrate, isocitrate and pyrophosphate, and the same pH were identical. This confirmed that urine does not contain an unidentified potent substance which inhibits the formation of calcium oxalate. Copyright © 1979, Wiley Blackwell. All rights reserved
引用
收藏
页码：253 / 255
页数：3
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