SELECTIVE DIFFERENTIATION OF CD4+ T-HELPER CELL SUBSETS

被引：108
|
作者：
SCOTT, P
机构：
[1] School of Veterinary Medicine, University of Pennsylvania, Philadelphia
来源：
CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 03期
关键词：
D O I：
10.1016/0952-7915(93)90058-Z
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
During the past year significant advances have been made in our understanding of the factors contributing to the differentiation of CD4+ T helper cell subsets. These have been driven, in part, by the realization that signals (cytokines) from the innate immune response are critical in T cell subset differentiation. In addition, several studies have also elucidated how the antigen-presenting cell, the antigenic epitope and the antigen concentration may contribute to the selective development of a particular T helper cell subset.
引用
收藏
页码：391 / 397
页数：7
相关论文
共 50 条
  • [1] The differentiation of CD4+ T-helper cell subsets in the context of helminth parasite infection
    Bouchery, Tiffany
    Kyle, Ryan
    Ronchese, Franca
    Le Gros, Graham
    FRONTIERS IN IMMUNOLOGY, 2014, 5
  • [2] Differentiation of CD4+ T-helper-cell subsets in leishmaniasis
    Scott, P
    T-CELL SUBSETS AND CYTOKINES INTERPLAY IN INFECTIOUS DISEASES, 1996, : 108 - 115
  • [3] MATURATION-DEPENDENT AND DIFFERENTIATION-DEPENDENT RESPONSIVENESS OF HUMAN CD4+ T-HELPER SUBSETS
    DEJONG, R
    BROUWER, M
    KUIPER, HM
    HOOIBRINK, B
    MIEDEMA, F
    VANLIER, RAW
    JOURNAL OF IMMUNOLOGY, 1992, 149 (08): : 2795 - 2802
  • [4] CLONAL ANALYSIS OF CD4+ T-HELPER CELL SUBSETS THAT INDUCE THE MONOCYTE PROCOAGULANT RESPONSE
    FAN, ST
    GLASEBROOK, AL
    EDGINGTON, TS
    CELLULAR IMMUNOLOGY, 1990, 128 (01) : 52 - 62
  • [5] Avidity of human T cell receptor engineered CD4+ T cells drives T-helper differentiation fate
    Adair, Patrick
    Kim, Yong Chan
    Pratt, Kathleen P.
    Scott, David W.
    CELLULAR IMMUNOLOGY, 2016, 299 : 30 - 41
  • [6] CLASSIFICATION OF CD4+ T-HELPER CELL CLONES IN HUMAN-MELANOMA
    GOEDEGEBUURE, PS
    LEE, KY
    MATORY, YL
    PEOPLES, GE
    YOSHINO, I
    EBERLEIN, TJ
    CELLULAR IMMUNOLOGY, 1994, 156 (01) : 170 - 179
  • [7] INDUCTION OF T-HELPER CELL SUBSETS
    ROCKEN, M
    MULLER, KM
    HAUSER, C
    SPRINGER SEMINARS IN IMMUNOPATHOLOGY, 1992, 13 (3-4): : 289 - 302
  • [8] Cytokines and transcription factors in the differentiation of CD4+ T helper cell subsets and induction of tissue inflammation and autoimmunity
    Pawlak, Mathias
    Ho, Allen W.
    Kuchroo, Vijay K.
    CURRENT OPINION IN IMMUNOLOGY, 2020, 67 : 57 - 67
  • [9] Early signaling events that underlie fate decisions of naive CD4+ T cells toward distinct T-helper cell subsets
    Yamane, Hidehiro
    Paul, William E.
    IMMUNOLOGICAL REVIEWS, 2013, 252 : 12 - 23
  • [10] Characterization of proteogenomic signatures of differentiation of CD4+ T cell subsets
    Kanno, Toshio
    Konno, Ryo
    Miyako, Keisuke
    Nakajima, Takahiro
    Yokoyama, Satoru
    Sasamoto, Shigemi
    Asou, Hikari K.
    Ohzeki, Junichiro
    Kawashima, Yusuke
    Hasegawa, Yoshinori
    Ohara, Osamu
    Endo, Yusuke
    DNA RESEARCH, 2023, 30 (01)
12345