A PROSPECTIVE AND RANDOMIZED STUDY COMPARING THE INCIDENCE OF INFUSION PHLEBITIS DURING CONTINUOUS AND CYCLIC PERIPHERAL PARENTERAL-NUTRITION

被引：29

作者：

KERIN, MJ ^{[1
]}

PICKFORD, IR ^{[1
]}

JAEGER, H ^{[1
]}

COUSE, NF ^{[1
]}

MITCHELL, CJ ^{[1
]}

MACFIE, J ^{[1
]}

机构：

[1] SCARBOROUGH GEN HOSP,JOINT GASTROENTEROL SERV,SCARBOROUGH,N YORKSHIRE,ENGLAND

来源：

CLINICAL NUTRITION | 1991年 / 10卷 / 06期

关键词：

D O I：

10.1016/0261-5614(91)90060-P

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Phlebitis is a major obstacle to successful and prolonged peripheral parenteral nutrition (PPN). This study evaluated the effects of elective changes of the intravenous cannula and cyclic infusion of PPN on the incidence and the severity of phlebitis. 51 consecutive patients requiring PPN were randomised into three groups. Group 1 received PPN continuously through a line which was changed only on evidence of phlebitis. In Group 2 intravenous lines were changed every 24h. Group 3 patients received PPN as a 12-h infusion after which the intravenous cannula was withdrawn. All patients received 1800 non-protein calories and 9.4 g nitrogen daily. Infusion sites were assessed daily for phlebitis and this was scored using a modified Maddox scale. The mean (range) duration of PPN was 7.5 (1-13), 10.0 (2-42) and 8.2 (3-14) days in the three groups respectively. Severe phlebitis occurred more frequently (p < 0.05) in Group 1 compared to Group 2 or Group 3. The overall incidence of phlebitis assessed from the mean value of the Maddox scores for each group was highest in Group 1 and was significantly greater than that observed in either Group 2 (p < 0.05) or Group 3 (p < 0.001). Group 3 patients who received cyclic PPN had the lowest incidence of phlebitis. The results of this study suggest that the incidence of infusion phlebitis is minimised during PPN by the cyclic infusion of nutrient solutions.

引用

页码：315 / 319

页数：5

共 22 条

[1]

Kaye, Smith, Complications of central venous cannulation, British Medical Journal, 297, pp. 572-573, (1988)

[2]

Mughal, Complications of intravenous feeding catheters, British Journal of Surgery, 76, pp. 15-21, (1989)

[3]

Lodge, Chisholm, Brennan, MacFie, Insertion technique, the key to avoiding infusion phlebitis: a prospective clinical trial, British Journal of Clinical Practice, 41, pp. 816-819, (1987)

[4]

Tomford, Hershey, McLaren, Porter, Cohen, Intravenous therapy team and peripheral venous catheter-associated complications, Archives of Internal Medicine, 144, pp. 1191-1194, (1984)

[5]

Hershey, Tomford, McLaren, Porter, Cohen, The natural history of intravenous catheter-associated phlebitis, Archives of Internal Medicine, 144, pp. 1373-1375, (1984)

[6]

Polak, Hydrocortisone in the prevention of transfusion thrombophlebitis, Lancet, 1, pp. 484-485, (1956)

[7]

Tanner, Delaney, Hennessy, The influence of heparin on intravenous infusions: a prospective study, British Journal of Surgery, 60, pp. 311-312, (1980)

[8]

Allcutt, Lort, McCollum, Final inline filtration for intravenous infusion: a prospective hospital study, British Journal of Surgery, 70, pp. 111-113, (1983)

[9]

Kohlhardt, Smith, Fine bore silicone catheters for peripheral intravenous nutrition in adults, British Medical Journal, 299, pp. 1380-1381, (1989)

[10]

Maddox, Rush, Rapp, Et al., Double-blind study to investigate methods to prevent cephalothin-induced phlebitis, American Journal of Hospital Pharmacy, 34, pp. 29-34, (1977)

← 1 2 3 →