HYDROXYLATED 2,3-DIARYLINDENES - SYNTHESIS, ESTROGEN-RECEPTOR BINDING-AFFINITY, AND BINDING ORIENTATION CONSIDERATIONS

被引:18
作者
ANSTEAD, GM [1 ]
PETERSON, CS [1 ]
KATZENELLENBOGEN, JA [1 ]
机构
[1] UNIV ILLINOIS,DEPT CHEM,BOX 37,1209 W CALIF ST,URBANA,IL 61801
关键词
D O I
10.1016/0022-4731(89)90235-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:877 / 887
页数:11
相关论文
共 32 条
[1]   FLUORESCENCE PROPERTIES OF 2,3-DIARYLINDENES [J].
ANSTEAD, GM ;
KATZENELLENBOGEN, JA .
JOURNAL OF PHYSICAL CHEMISTRY, 1988, 92 (22) :6249-6258
[2]   OPTIMIZING OF 2,3-DIARYLINDENES AS FLUORESCENT ESTROGENS - VARIATION OF THE ACCEPTOR GROUP, ORTHO SUBSTITUTION OF THE 2-RING, AND C-1 METHYLATION [J].
ANSTEAD, GM ;
KATZENELLENBOGEN, JA .
JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (09) :1754-1761
[3]   2,3-DIARYLINDENES AND 2,3-DIARYLINDENONES - SYNTHESIS, MOLECULAR-STRUCTURE, PHOTOCHEMISTRY, ESTROGEN-RECEPTOR BINDING-AFFINITY, AND COMPARISONS WITH RELATED TRIARYLETHYLENES [J].
ANSTEAD, GM ;
ALTENBACH, RJ ;
WILSON, SR ;
KATZENELLENBOGEN, JA .
JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (07) :1316-1326
[4]  
ANSTEAD GM, 1987, 194TH NAT M AM CHEM
[5]  
ANSTEAD GM, 1989, IN PRESS J MED CHEM
[6]  
ANSTEAD GM, 1989, IN PRESS PHOTOCHEM P
[7]  
BARRANS PY, 1979, ACTA CRYSTALLOGR B, V35, P2271
[8]   1,2-DIARYL-3,4-DIHYDRONAPHTHALENES - PHOTOFLUOROGENIC LIGANDS FOR THE ESTROGEN-RECEPTOR [J].
BINDAL, RD ;
KATZENELLENBOGEN, JA .
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1985, 23 (6A) :929-937
[9]   1,2-BIS(4-HYDROXYPHENYL)-3,4-DIHYDRO-6-HYDROXYNAPHTHALENE, A PHOTOFLUOROGENIC LIGAND FOR THE ESTROGEN-RECEPTOR [J].
BINDAL, RD ;
KATZENELLENBOGEN, JA .
PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1986, 43 (02) :121-126
[10]   MOLECULAR ADDITION-COMPOUNDS .3. REDISTRIBUTION OF BORANE-METHYL SULFIDE WITH BORON TRICHLORIDE-METHYL SULFIDE AND BORON TRIBROMIDE-METHYL SULFIDE AS CONVENIENT ROUTES TO CORRESPONDING HALOBORANE-METHYL SULFIDES [J].
BROWN, HC ;
RAVINDRAN, N .
INORGANIC CHEMISTRY, 1977, 16 (11) :2938-2940