RISK-FACTORS FOR FALLS AS A CAUSE OF HIP FRACTURE IN WOMEN

被引:644
作者
GRISSO, JA
KELSEY, JL
STROM, BL
CHIU, GY
MAISLIN, G
OBRIEN, LA
HOFFMAN, S
KAPLAN, F
机构
[1] COLUMBIA UNIV,DIV EPIDEMIOL,NEW YORK,NY 10027
[2] HOSP UNIV PENN,DEPT ORTHOPED,PHILADELPHIA,PA 19104
关键词
D O I
10.1056/NEJM199105093241905
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. Although even in the elderly most falls are not associated with fractures, over 90 percent of hip fractures are the result of a fall. Few studies have assessed whether the risk factors for falls are also important risk factors for hip fracture. Methods. To examine the importance of risk factors for falls in the epidemiology of hip fracture, we performed a case-control study of 174 women (median age, 80 years) admitted with a first hip fracture to 1 of 30 hospitals in New York and Philadelphia. Controls, matched to the case patients according to age and hospital, were selected from general surgical and orthopedic surgical hospital services. Information was obtained by direct interview. Results. As measured by the odds ratio, increased risks for hip fracture were associated with lower-limb dysfunction (odds ratio = 1.7; 95 percent confidence interval, 1.1 to 2.8), visual impairment (odds ratio = 5.1; 95 percent confidence interval, 1.9 to 13.9), previous stroke (odds ratio = 2.0; 95 percent confidence interval, 1.0 to 4.0), Parkinson's disease (odds ratio = 9.4; 95 percent confidence interval, 1.2 to 76.1), and use of long-acting barbiturates (odds ratio = 5.2; 95 percent confidence interval, 0.6 to 45.0). Of the controls, 44 (25 percent) had had a recent fall. The case patients were more likely than these controls to have fallen from a standing height or higher (odds ratio = 2.4; 95 percent confidence interval, 1.0 to 5.7). Of those with hip fracture the younger patients (< 75 years old) were more likely than the older ones (greater-than-or-equal-to 75 years old) to have fallen on a hard surface (odds ratio = 1.9; 95 percent confidence interval, 1.04 to 3.7). Conclusions. A number of factors that have been identified as risk factors for falls are also associated with hip fracture, including lower-limb dysfunction, neurologic conditions, barbiturate use, and visual impairment. Given the prevalence of these problems among the elderly, who are at highest risk, programs to prevent hip fracture should include measures to prevent falls in addition to measures to slow bone loss.
引用
收藏
页码:1326 / 1331
页数:6
相关论文
共 41 条
  • [1] ALFFRAM PER-AXEL, 1964, ACTA ORTHOPAED SCAND SUPPL, V65, P1
  • [2] BASTOW MD, 1983, LANCET, V1, P143
  • [3] BRESLOW NE, 1980, IARC SCI PUBL, V32, P373
  • [4] FALLS AND FRACTURES IN PATIENTS WITH ALZHEIMER-TYPE DEMENTIA
    BUCHNER, DM
    LARSON, EB
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1987, 257 (11): : 1492 - 1495
  • [5] FACTORS IN FRACTURE OF FEMALE FEMUR - A CLINICAL STUDY OF ENVIRONMENTAL PHYSICAL MEDICAL AND PREVENTATIVE ASPECTS OF THIS INJURY
    CLARK, ANG
    [J]. GERONTOLOGIA CLINICA, 1968, 10 (05): : 257 - +
  • [6] PHYSICAL-ACTIVITY, MUSCLE STRENGTH, AND CALCIUM INTAKE IN FRACTURE OF THE PROXIMAL FEMUR IN BRITAIN
    COOPER, C
    BARKER, DJP
    WICKHAM, C
    [J]. BRITISH MEDICAL JOURNAL, 1988, 297 (6661) : 1443 - 1446
  • [7] CUMMINGS SR, 1989, J GERONTOL, V44, pM107
  • [8] EPIDEMIOLOGY OF OSTEOPOROSIS AND OSTEOPOROTIC FRACTURES
    CUMMINGS, SR
    KELSEY, JL
    NEVITT, MC
    ODOWD, KJ
    [J]. EPIDEMIOLOGIC REVIEWS, 1985, 7 : 178 - 208
  • [9] ANTHROPOMETRIC INDICATORS AND HIP FRACTURE - THE NHANES-I EPIDEMIOLOGIC FOLLOW-UP-STUDY
    FARMER, ME
    HARRIS, T
    MADANS, JH
    WALLACE, RB
    CORNONIHUNTLEY, J
    WHITE, LR
    [J]. JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1989, 37 (01) : 9 - 16
  • [10] FELSON DT, 1988, AM J EPIDEMIOL, V128, P1102