SYNTHESIS OF DIARYLKETONES THROUGH CARBONYLATIVE COUPLING

Carbonylative coupling reactions leading to diarylketones using a carbon monoxide source and aryl halides or aryl metals are reviewed. Palladium-catalysed reactions between an aryl halide (or pseudohalide) and an aryl metal of group IIB, IIA, or IVA can be carried out under mild conditions, in particular using low carbon monoxide pressure. However, many challenges remain and significant new results (the design of more efficient systems) and applications (the synthesis of important target molecules) are to be expected in the near future.