ABNORMALITIES OF T-CELL IMMUNOREGULATION IN HEMORRHAGIC-FEVER WITH RENAL SYNDROME

被引：44

作者：

CHEN, LB

YANG, WS

机构：

[1] Department of Infectious Diseases, Second Teaching Hospital, Fourth Military Medical University, Xi’an

来源：

JOURNAL OF INFECTIOUS DISEASES | 1990年 / 161卷 / 05期

关键词：

D O I：

10.1093/infdis/161.5.1016

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The functions of spontaneous suppressor T cells and T lymphocyte subsets in patients with hemorrhagic fever with renal syndrome were compared. In the early stages of disease, decreased activity of spontaneous suppressor T cells was concurrent with increased numbers of CD8+ cells and a reversed CD4:CD8 ratio. These changes were related to abnormalities in serum C3 level and circulating immune complexes. In the recovery stages of the illness, spontaneous suppressor T cell activity and T cell subsets returned to normal levels. © 1990 by the University of Chicago. All rights reserved.

引用

页码：1016 / 1019

页数：4

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