INTERACTION BETWEEN PROFLAVIN AND DEOXYTETRARIBONUCLEOSIDE TRIPHOSPHATE 5'-D(APGPCPT) - THERMODYNAMIC ANALYSIS ACCORDING TO H-1-NMR DATA

被引：0
|
作者：
VESELKOV, AN [1 ]
DEVIS, D [1 ]
DYMANT, LN [1 ]
PARKES, H [1 ]
SHIPP, D [1 ]
机构：
[1] UNIV LONDON BIRKBECK COLL,LONDON WC1E 7HX,ENGLAND
来源：
BIOFIZIKA | 1992年 / 37卷 / 05期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
Temperature relationships of chemical shifts of protons of proflavin mixed with deoxytetraribonucleoside triphosphate 5'-d(ApGpCpT) in water solution were investigated on impulse NMR spectrometer (500 MHz). Procedure is suggested for calculating values of mole fractions of various associates in solution as a function against temperature. Free energies of Gibbs, entalpy and entropy were determined in the reactions of complex formation 1 : 1, 1 : 2, 2 : 1 of proflavin with tetranucleotide. The results point to a significant role of hydrophobic interactions during the formation of dye - tetramere duplex complexes.
引用
收藏
页码：851 / 858
页数：8
相关论文
共 50 条
  • [21] EFFECT OF RECRYSTALLIZATION IN TRICALCIUM SILICATE HYDRATE ACCORDING TO H-1-NMR SPIN-RELAXATION DATA
    BOROVIK, AY
    KRIGER, YG
    RINSKAYA, LI
    TYULENEVA, NI
    JOURNAL OF STRUCTURAL CHEMISTRY, 1990, 31 (03) : 495 - 497
  • [22] H-1-NMR STUDY OF THE BINDING OF BIS(ACRIDINES) TO D(AT)5.D(AT)5 .1. MODE OF BINDING
    ASSAMUNT, N
    DENNY, WA
    LEUPIN, W
    KEARNS, DR
    BIOCHEMISTRY, 1985, 24 (06) : 1441 - 1449
  • [23] Thermodynamic analysis of the antibiotic mitoxantrone with the deoxytetranucleotide 5′-d(TpGpCpA) in aqueous solutions, based on 1H NMR spectroscopy data
    Veselkov, AN
    Evstigneev, MP
    Vysotskii, SA
    Veselkov, DA
    Davis, DB
    BIOFIZIKA, 2002, 47 (03): : 459 - 466
  • [24] H-1-NMR STUDY OF INTERACTION BETWEEN CARBAZOLE DERIVATIVES AND ELECTRON-ACCEPTOR MOLECULES
    XU, GZ
    WANG, YZ
    YANG, QW
    KEXUE TONGBAO, 1982, 27 (11): : 1246 - 1247
  • [25] NMR-SPECTROSCOPY IN PHARMACEUTICAL ANALYSIS .5. H-1-NMR SPECTROSCOPIC IDENTIFICATION OF CEPHALOSPORINE ANTIBIOTICS
    KARTASHOV, VS
    CHERNYSHEV, AI
    POLISAR, RD
    YESIPOV, SY
    ARZAMASTSEV, AP
    KHIMIKO-FARMATSEVTICHESKII ZHURNAL, 1990, 24 (05): : 85 - 88
  • [26] H-1-NMR STUDY OF THE BINDING OF BIS(ACRIDINES) TO D(AT)5.D(AT)5 .2. DYNAMIC ASPECTS
    ASSAMUNT, N
    LEUPIN, W
    DENNY, WA
    KEARNS, DR
    BIOCHEMISTRY, 1985, 24 (06) : 1449 - 1460
  • [27] SUPRAMOLECULAR INTERACTION BETWEEN ADENOSINE 5'-TRIPHOSPHATE (ATP) AND POLYCHARGED TETRAAZAMACROCYCLES - THERMODYNAMIC AND P-31 NMR-STUDIES
    BIANCHI, A
    MICHELONI, M
    PAOLETTI, P
    INORGANICA CHIMICA ACTA-BIOINORGANIC CHEMISTRY, 1988, 151 (04): : 269 - 272
  • [28] H-1-NMR STUDIES ON THE SPECIFICITY OF THE INTERACTION BETWEEN BOVINE PANCREATIC RIBONUCLEASE-A AND DIDEOXYNUCLEOSIDE MONOPHOSPHATES
    ALONSO, J
    PAOLILLO, L
    DAURIA, G
    NOGUES, MV
    CUCHILLO, CM
    INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 1988, 31 (06): : 537 - 543
  • [29] Analysis of the interaction of ethidium bromide with a DNA octamer 5’-d(GpApCpApTpGpTpC) in aqueous solution using1H NMR data
    A. N. Veselkov
    L. N. Djimant
    V. I. Pakhomov
    S. G. Osetrov
    A. Tucker
    D. B. Davies
    Journal of Structural Chemistry, 1999, 40 : 220 - 229
  • [30] Analysis of the interaction of ethidium bromide with a DNA octamer 5′-d(GpApCpApTpGpTpC) in aqueous solution using 1H NMR data
    Veselkov, AN
    Djimant, LN
    Pakhomov, VI
    Osetrov, SG
    Tucker, A
    Davies, DB
    JOURNAL OF STRUCTURAL CHEMISTRY, 1999, 40 (02) : 220 - 229
12345