ALTERED RESPONSE TO APOMORPHINE AND HALOPERIDOL AFTER 9 DAYS OF COCAINE INJECTIONS

被引:7
作者
EPSTEIN, PN [1 ]
ALTSHULER, HL [1 ]
机构
[1] BAYLOR UNIV,COLL MED,TEXAS MED CTR,HOUSTON,TX 77030
关键词
Apomorphine; Catalepsy; Cocaine; Haloperidol; Stereotype; Tolerance;
D O I
10.1016/0091-3057(79)90085-6
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Sprague Dawley rats, pretreated with nine daily injections of 20 mg/Kg cocaine or saline, were evaluated for aspects of their behavioral response to apomorphine, haloperidol, or cocaine, twenty-four hours after their last pretreatment injection. Data obtained from saline and cocaine pretreated animals indicated that: cocaine pretreated rats were more sensitive to haloperidol-induced catalepsy, less responsive to some of the stereotypic effects of apomorphine and similar in their responses to the anticataleptic properties of cocaine. © 1979.
引用
收藏
页码:189 / 193
页数:5
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