While the majority of capillary electrophoresis (CE) applications to date have been concerned with the separation of biological molecules, this methodology also appears to be a viable alternative to ion chromatography (IC) for the determination of inorganic ions and other low-molecular-mass ionic solutes. CE offers a number of advantages over IC, including simplicity, greater separation efficiency, unique selectivity and a high degree of matrix independence, all of which make it ideal for the analysis of ionic solutes in complex samples.