PHOTOREACTIVATION OF PYRIMIDINE DIMERS IN DNA FROM THYROID-CELLS OF THE TELEOST, POECILIA-FORMOSA

被引：52

作者：

ACHEY, PM ^{[1
]}

WOODHEAD, AD ^{[1
]}

SETLOW, RB ^{[1
]}

机构：

[1] BROOKHAVEN NATL LAB,DEPT BIOL,UPTON,NY 11973

来源：

PHOTOCHEMISTRY AND PHOTOBIOLOGY | 1979年 / 29卷 / 02期

关键词：

D O I：

10.1111/j.1751-1097.1979.tb07053.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Abstract— We have developed and used a simple technique to estimate the quantity of pyrimidine dimers in unlabeled cellular DNA. DNA is extracted from cells, treated with an endonuclease specific for dimers, and its molecular weight estimated by its electrophoretic mobility on alkaline agarose slab gels. The technique is used to show that cells from thyroid tissue of the fish Poecilia formosa have photoreactivating activity towards dimers in the cellular DNA. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：305 / 310

页数：6

共 13 条

[1] DIFFERENT RATE-LIMITING STEPS IN EXCISION REPAIR OF ULTRAVIOLET-DAMAGED AND N-ACETOXY-2-ACETYLAMINOFLUORENE-DAMAGED DNA IN NORMAL HUMAN FIBROBLASTS [J].