HISTOPATHOLOGICAL EVALUATION OF NEOPLASTIC AND NON-NEOPLASTIC BONE TUMOURS IN A TEACHING HOSPITAL

BACKGROUND Bone tumours are comparatively uncommon among wide array of lesions and pose a diagnostic problem. Definitive clinical diagnosis of bone lesion is often difficult. So it is essential to identify the lesion correctly before deciding the line of treatment. For the correct diagnosis of bone lesions, charting out treatment plan and estimating prognosis, interpretation of biopsy material proves to be indispensable. Aim of the study is to study histopathological features of bone lesions and their correlation with age of presentation, site and type of lesion. MATERIALS AND METHODS The duration of the study was 2 years [June 2014-May 2016]. A review of histopathological reports of all bone specimens received in the Department of Pathology, SVS Medical College over a period of 2 years was done. A total of 46 bone lesions were analysed. Bone biopsy was performed by either percutaneous method with needle/drill or open surgical biopsy. If attached soft tissue was also received, bony tissues were put for decalcification (10% nitric acid). Soft tissue was immediately fixed into 10 % formalin and processed by paraffin embedding. Sections were stained by haematoxylin and eosin stain and microscopic examination was done. RESULTS Total non-neoplastic bone lesions were 18 (39.1 %) while that of neoplastic lesions were 28 (60.9%). Both neoplastic and nonneoplastic lesions were more prevalent in < 20 years age group. Among the non-neoplastic lesions, osteomyelitis lesions (38.9%) were the commonest while giant cell tumour (42.8%) was common neoplastic lesions. Overall most common bone involved was femur. CONCLUSION Though bone tumours are less common lesions and pose a diagnostic problem, if viewed in perspective of clinico-radiology and histopathology, a correct diagnosis can be reached.