A New 5 alpha, 8 alpha-Epidioxy Sterol from the Marine Sponge Plakortis simplex

被引：2

作者：

Oh, Jung Soon ^{[1
]}

Kim, Myoung Ha ^{[1
]}

Song, Ah Rin ^{[1
]}

Rho, Jung-Rae ^{[1
]}

机构：

[1] Kunsan Natl Univ, Dept Oceanog, Jeonbuk 573701, South Korea

来源：

JOURNAL OF THE KOREAN MAGNETIC RESONANCE SOCIETY | 2010年 / 14卷 / 01期

关键词：

ID and 2D NMR; Plakortis simplex; 5,8-epidioxy sterol; C-24; configuration;

D O I：

10.6564/JKMRS.2010.14.1.001

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Four 5,8-epidioxy sterols were isolated from the marine sponge Plakortis simplhfy. Their structures were completely determined by an extensive NMR analysis and comparison with NMR data of' similar compounds for absolute stereochemistry of the side chain. The compounds were assigned as 5,8-epidioxy( 24S)-ethylcholesta-6,22(E), 25-trien-3-ol(1), 5,8-epidioxy-(24S)-methylcholesta6,22( E)-dien-3-ol(2), 5,8-epidioxycholesta-6,22(E)-dien-3-ol(3) and 5,8epidioxycholesta- 6-cn-3-ol (4).

引用

页码：1 / 8

页数：8

共 12 条

[1] STEROLS OF CAJANUS-CAJAN AND 3 OTHER LEGUMINOSAE SEEDS [J].

AKIHISA, T ;

NISHIMURA, Y ;

NAKAMURA, N ;

ROY, K ;

GHOSH, P ;

THAKUR, S ;

TAMURA, T .

PHYTOCHEMISTRY, 1992, 31 (05) :1765-1768

[2] Marine natural products [J].

Blunt, John W. ;

Copp, Brent R. ;

Hu, Wan-Ping ;

Munro, Murray H. G. ;

Northcote, Peter T. ;

Prinsep, Michele R. .

NATURAL PRODUCT REPORTS, 2009, 26 (02) :170-244

[3] Sterols from Teucrium abutiloides and T-betonicum [J].

Gaspar, H ;

Palma, FMSB ;

delaTorre, MC ;

Rodriguez, B .

PHYTOCHEMISTRY, 1996, 43 (03) :613-615

[4] Sarcotrine G, a New Derivative Isolated from a Marine Sponge Sarcotragus Species [J].

Hwang, Buyng Su ;

Park, Su Young ;

Park, Myung Gil ;

Rho, Jung-Rae .

JOURNAL OF THE KOREAN MAGNETIC RESONANCE SOCIETY, 2008, 12 (01) :33-39

[5] A NEW 5-ALPHA,8-ALPHA-EPIDIOXY STEROL FROM THE OKINAWAN MARINE SPONGE OF THE AXINYSSA GENUS [J].

IGUCHI, K ;

SHIMURA, H ;

YANG, Z ;

YAMADA, Y .

STEROIDS, 1993, 58 (09) :410-413

[6] New biologically active marine sesquiterpenoid and steroid from the Okinawan sponge of the genus Axinyssa [J].

Iwashima, M ;

Terada, I ;

Iguchi, K ;

Yamori, T .

CHEMICAL & PHARMACEUTICAL BULLETIN, 2002, 50 (09) :1286-1289

[7] 26,27-cyclosterols and other polyoxygenated sterols from a marine sponge Topsentia sp. [J].

Luo, Xuan ;

Li, Famei ;

Shinde, Pramod B. ;

Hong, Jongki ;

Lee, Chong-O. ;

Im, Kwang Sik ;

Jung, Jee H. .

JOURNAL OF NATURAL PRODUCTS, 2006, 69 (12) :1760-1768

[8]

Park SY, 2007, J KOREAN MAGN RESON, V11, P122

[9] Isolation of ergosterol peroxide and its reversion to ergosterol in the pathogenic fungus Sporothrix schenckii [J].

Da Graça Sgarbi D.B. ;

Da Silva A.J.R. ;

Carlos I.Z. ;

Silva C.L. ;

Angluster J. ;

Alviano C.S. .

Mycopathologia, 1997, 139 (1) :9-14

[10] STEROIDS FROM SPONGES [J].

SHEIKH, YM ;

DJERASSI, C .

TETRAHEDRON, 1974, 30 (23-2) :4095-4103

← 1 2 →