AN OUTBREAK OF HEPATITIS-A IN YOUNG-ADULTS IN CENTRAL ITALY

被引:24
作者
STROFFOLINI, T
BIAGINI, W
LORENZONI, L
PALAZZESI, GP
DIVIZIA, M
FRONGILLO, R
机构
[1] OSPED TERNI,DIREZIONE SANITARIA,TERNI,ITALY
[2] OSPED TERNI,SERV IMMUNOEMATOL,TERNI,ITALY
[3] UNIV ROME 2,IST IGIENE & MED PREVENT,ROME,ITALY
[4] UNIV PERUGIA,MALATTIE INFETT CLIN,TERNI,ITALY
关键词
Adults; Hepatitis A; Outbreak;
D O I
10.1007/BF00145788
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Between September, 1988 and January, 1989 a common source outbreak of 47 cases of serologically confirmed hepatitis A occurred in a town of central Italy. Thirty-eight cases were primary, three co-primary and six secondary. The highest age-specific attack rate was seen in subjects aged 15-24 years (120 per 100,000); the mean age of cases was 24.6 years and the median age was 22 years. A matched triplet case-control study showed significant association between the disease and consumption of either raw mussels (41% of cases, compared with 10% of controls; P < 0.0001) or a single brand of mineral water (63% of cases, compared with 41% of controls; P < 0.05). The mean age of the cases reflects the shift in primary susceptibility to the infection from younger to older age groups, a finding which has recently been demonstrated by several seroepidemiological surveys in Italy. © 1990 Gustav Fischer.
引用
收藏
页码:156 / 159
页数:4
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