High-flow nasal cannula oxygen therapy for acute exacerbation of interstitial pneumonia: A case series

被引：22

作者：

Horio, Yukihiro ^{[1
]}

Takihara, Takahisa ^{[1
]}

Niimi, Kyoko ^{[1
]}

Komatsu, Masamichi ^{[2
]}

Sato, Masako ^{[1
]}

Tanaka, Jun ^{[1
]}

Takiguchi, Hiroto ^{[1
]}

Tomomatsu, Hiromi ^{[1
]}

Tomomatsu, Katsuyoshi ^{[1
]}

Hayama, Naoki ^{[1
]}

Oguma, Tsuyoshi ^{[1
]}

Aoki, Takuya ^{[1
]}

Urano, Tetsuya ^{[1
]}

Takagi, Atsushi ^{[2
]}

Asano, Koichiro ^{[1
]}

机构：

[1] Tokai Univ, Sch Med, Dept Med, Div Pulm Med, 143 Shimokasuya, Isehara, Kanagawa 2591193, Japan

[2] Tokai Univ, Sch Med, Dept Med, Div Gen Med, Isehara, Kanagawa, Japan

来源：

RESPIRATORY INVESTIGATION | 2016年 / 54卷 / 02期

关键词：

Interstitial pneumonia; Acute exacerbation; Acute respiratory failure; Oxygen therapy; High-flow nasal cannula;

D O I：

10.1016/j.resinv.2015.09.005

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

We report 3 cases (all men, age: 69-81 years) of acute exacerbation of interstitial pneumonia (AEIP) that were successfully treated with a high-flow nasal cannula (HFNC), which delivers heated, humidified gas at a fraction of inspired oxygen (FIO2) up to 1.0 (100%). Oxygenation was insufficient under non-rebreathing face masks; however, the introduction of HFNC with an FIO2 of 0.7-1.0 (flow rate: 40 L/min) improved oxygenation and was well-tolerated until the partial pressure of oxygen in blood/FIO2 ratio increased (between 21 and 26 days). Thus, HFNC might be an effective and well-tolerated therapeutic addition to the management of AEIP. (C) 2015 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.

引用

页码：125 / 129

页数：5

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