ANODIC AMIDE OXIDATIONS - CONFORMATIONALLY RESTRICTED PEPTIDE BUILDING-BLOCKS FROM THE DIRECT OXIDATIONS OF DIPEPTIDES

被引：26
作者：
CORNILLE, F
FOBIAN, YM
SLOMCZYNSKA, U
BEUSEN, DD
MARSHALL, GR
MOELLER, KD
机构：
[1] WASHINGTON UNIV,DEPT MOLEC BIOL & PHARMACOL,ST LOUIS,MO 63130
[2] WASHINGTON UNIV,DEPT CHEM,ST LOUIS,MO 63130
[3] WASHINGTON UNIV,CTR MOLEC DESIGN,ST LOUIS,MO 63130
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 38期
关键词：
D O I：
10.1016/0040-4039(94)88206-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A pair of bicyclic lactam based conformationally restricted peptide mimetics have been synthesized in good yield by the direct anodic oxidation of dipeptides. This work highlights the simplicity of using electrochemistry to construct peptide mimetics and serves to further define the nature of the substituents that are compatible with an electrochemical procedure for annulating rings onto amino acid derivatives.
引用
收藏
页码：6989 / 6992
页数：4
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