Influence of gut bacteria on development and progression of non-alcoholic fatty liver disease

被引:28
作者
Abdul-Hai, Ali [1 ]
Abdallah, Ali [1 ]
Malnick, Stephen D. H. [1 ]
机构
[1] Hebrew Univ Jerusalem, Kaplan Med Ctr, Div Internal Med, 1 Pasternak, IL-76100 Rehovot, Israel
关键词
Microbiome; Metabolic syndrome; Stool transplantation; Non-alcoholic fatty liver disease;
D O I
10.4254/wjh.v7.i12.1679
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The intestine of the human contains a dynamic population of microbes that have a symbiotic relationship with the host. In addition, there is an effect of the intestinal microbiota on metabolism and digestion. Non-alcoholic fatty liver disease (NAFLD) is a common cause worldwide of hepatic pathology and is thought to be the hepatic manifestation of the metabolic syndrome. In this review we examine the effect of the human microbiome on the components and pathogenesis of the metabolic syndrome. We are now on the threshold of therapeutic interventions on the human microbiome in order to effect human disease including NAFLD.
引用
收藏
页码:1679 / 1684
页数:6
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