REGULATION OF CORNEAL COLLAGENASE PRODUCTION - STIMULATION OF SERIALLY PASSAGED STROMAL CELLS BY BLOOD MONONUCLEAR-CELLS

被引：36

作者：

NEWSOME, DA ^{[1
]}

GROSS, J ^{[1
]}

机构：

[1] HARVARD UNIV, SCH MED, DEPT MED, BOSTON, MA 02115 USA

来源：

CELL | 1979年 / 16卷 / 04期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0092-8674(79)90104-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

After three or more passages, stromal cell out-growths from explants of normal rabbit corneas and from corneas previously burned with alkali did not produce collagenase until they were stimulated by the addition of rabbit blood-derived mononuclear cells or media conditioned by them. Normal stromal cells required stimulation by lymphocytes or their products from alkali-burned animals, whereas those from alkali-burned corneas were stimulated by lymphocytes from either normal or alkali-burned rabbits. © 1979.

引用

页码：895 / 900

页数：6

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