The Use of High-dose Insulin Infusion and Lipid Emulsion Therapy in Concurrent Beta-blocker and Calcium Channel Blocker Overdose

被引：8

作者：

Lashari, Bilal H. ^{[1
]}

Minalyan, Artem ^{[2
]}

Khan, Waqas ^{[2
]}

Naglak, Mary ^{[3
]}

Ward, William ^{[4
]}

机构：

[1] Abington Hosp Jefferson Hlth, Internal Med, Abington, PA USA

[2] Abington Jefferson Hlth, Internal Med, Abington, PA 19001 USA

[3] Abington Jefferson Hlth, Med, Abington, PA USA

[4] Abington Hosp Jefferson Hlth, Pulmonol & Crit Care, Abington, PA USA

来源：

CUREUS | 2018年 / 10卷 / 11期

关键词：

calcium channel blockers; beta blockers; lipid emulsion therapy; high-dose insulin;

D O I：

10.7759/cureus.3534

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Patients admitted with the presumed coingestion of beta-blockers (BBs) and calcium channel blockers (CCBs) should be initially managed in accordance with standardized resuscitation protocols (the airway, breathing, and circulation (ABC) approach). Additionally, more specific interventions should be promptly attempted. Intravenous glucagon and calcium salts have long been used in the treatment of BB and CCB toxicities. We present a case of a severe, concurrent BB and CCB toxicity resulting in cardiovascular collapse refractory to vasopressors. The administration of high-dose insulin (HDI) and lipid emulsion therapy (LET) resulted in a significant improvement in hemodynamics with an overall favorable outcome in the patient.

引用

页数：6

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