CURRENT CONCEPTS IN PSORIATIC-ARTHRITIS

被引:9
作者
VEYS, EM
MIELANTS, H
机构
关键词
PSORIASIS; PSORIATIC ARTHRITIS;
D O I
10.1159/000246987
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Psoriatic arthritis is an inflammatory arthropathy associated with psoriasis and characterized by absence of rheumatoid factor. Any form of psoriasis can be complicated by joint inflammation. Four groups have been identified: pauciarticular psoriatic arthritis, psoriatic spondylitis, symmetrical polyarticular psoriatic arthritis and arthritis mutilans. The etiology of psoriatic arthritis remains unclear. Genetic, immunologic and environmental factors are thought to be important in the development of the disease. The role of cytokines and adhesion molecules in the mechanism of joint destruction is highlighted, and recent therapeutic strategies are discussed.
引用
收藏
页码:35 / 41
页数:7
相关论文
共 24 条
[1]  
AGILAR JL, 1991, ARTHRITIS RHEUM, V34, pS194
[2]  
ALONSO JCT, 1991, BRIT J RHEUMATOL, V30, P245
[3]   LIVER-ENZYME LEVELS IN ARTHRITIS PATIENTS TREATED WITH LONG-TERM BOLUS METHOTREXATE [J].
APONTE, J ;
PETRELLI, M ;
VONDAWSON, N .
ARTHRITIS AND RHEUMATISM, 1992, 35 (01) :126-127
[4]  
Biondi Oriente C, 1989, Acta Derm Venereol Suppl (Stockh), V146, P69
[5]  
BRANCATO L, 1989, RHEUMATOL INT, V9, P137
[6]  
DOUGADOS M, UNPUB SULFASALAZINE
[7]  
ESPINOZA LR, 1992, J RHEUMATOL, V19, P872
[8]  
FARR M, 1990, BRIT J RHEUMATOL, V29, P46
[9]   ASPIRIN, HYDROXYCHLOROQUINE, AND HEPATIC ENZYME ABNORMALITIES WITH METHOTREXATE IN RHEUMATOID-ARTHRITIS [J].
FRIES, JF ;
SINGH, G ;
LENERT, L ;
FURST, DE .
ARTHRITIS AND RHEUMATISM, 1990, 33 (11) :1611-1619
[10]  
GLADMAN DD, 1987, Q J MED, V62, P127