B-RAF AND A B-RAF PSEUDOGENE ARE LOCATED ON 7Q IN MAN

被引：1
|
作者：
SITHANANDAM, G
DRUCK, T
CANNIZZARO, LA
LEUZZI, G
HUEBNER, K
RAPP, UR
机构：
[1] NCI,FREDERICK CANC RES & DEV CTR,VIRAL CARCINOGENESIS LAB,FREDERICK,MD 21702
[2] PRI DYNCORP,FREDERICK CANC RES & DEV CTR,BIOL CARCINOGENESIS & DEV PROGRAM,FREDERICK,MD 21702
[3] TEMPLE UNIV,HLTH SCI CTR,SCH MED,FELS INST CANC RES & MOLEC BIOL,PHILADELPHIA,PA 19140
来源：
ONCOGENE | 1992年 / 7卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The B-raf gene was lozalized to human chromosome region 7p11-7qter by Southern blot analysis of its segregation in a panel of rodent-human hybrids, using a B-raf cDNA clone. Chromosomal in situ hybridization refined the localization to 7q33-36. Analysis of genomic B-raf clones identified a B-raf pseudogene in addition to the active gene. Based on the chromosomal mapping data we conclude that the pseudogene is located near the active gene.
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页码：795 / 799
页数：5
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