CHROMATIN AND HISTONES - BINDING OF TRITIATED ACTINOMYCIN D TO HETEROCHROMATIN IN MEALY BUGS

被引：79
作者：
BERLOWITZ, L
PALLOTTA, D
SIBLEY, CH
机构：
[1] Department of Biology, State University of New York, Buffalo, NY
来源：
SCIENCE | 1969年 / 164卷 / 3887期
关键词：
D O I：
10.1126/science.164.3887.1527
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
The degree of actinomycin D binding to DNA in chromatin is dependent upon the state of repression of chromatin. Living cells bind three times more tritiated actinomycin to euchromatin than to genetically inactive heterochromatin. Extraction of histone results in a general increase in tritiated actinomycin binding and in a ratio of the uptake in heterochromatin to that in euchromatin approaching unity.
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页码：1527 / +
页数：1
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