SUSCEPTIBILITY OF MELANIZED AND NONMELANIZED CRYPTOCOCCUS-NEOFORMANS TO NITROGEN-DERIVED AND OXYGEN-DERIVED OXIDANTS

被引：184

作者：

WANG, YL

CASADEVALL, A

机构：

[1] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT MED,DIV INFECT DIS,BRONX,NY 10461

[2] YESHIVA UNIV ALBERT EINSTEIN COLL MED,DEPT MICROBIOL & IMMUNOL,BRONX,NY 10461

来源：

INFECTION AND IMMUNITY | 1994年 / 62卷 / 07期

关键词：

D O I：

10.1128/IAI.62.7.3004-3007.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Melanized Cryptococcus neoformans cells were less susceptible than nonmelanized cells to the fungicidal effects of nitrogen- and oxygen-derived oxidants. The results support the hypothesis that the phenoloxidase enzyme system contributes to virulence by protecting C. neoformans against nitrogen- and oxygen-derived oxidative antimicrobial molecules produced by immune effector cells.

引用

页码：3004 / 3007

页数：4

共 36 条

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