REAL-TIME CONFOCAL LASER SCAN MICROSCOPE FOR EXAMINATION AND DIAGNOSIS OF THE EYE IN-VIVO

被引：22

作者：

MASSIG, JH

PREISSLER, M

WEGENER, AR

GAIDA, G

机构：

[1] CARL ZEISS AG, W-7082 OBERKOCHEN, GERMANY

[2] UNIV BONN, EXPTL OPHTHALMOL ABT, W-5300 BONN 1, GERMANY

来源：

APPLIED OPTICS | 1994年 / 33卷 / 04期

关键词：

CONFOCAL MICROSCOPY; LASER SCANNING; EYE; IN-VIVO IMAGING;

D O I：

10.1364/AO.33.000690

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A confocal laser scan microscope is designed for the diagnosis and the examination of the anterior segment of the human eye in vivo. Any contact of the eye with the instrument optics or an immersion fluid is avoided to preclude the risk of infection or injury. Normal eyes of nine volunteers are observed and investigated. Nerve fibers and keratocytes in the stroma and the endothelium of the cornea, the capsule, and the suture of the lens, and threadlike structures in the vitreous can be observed. Cellular details in all tissues investigated can be resolved.

引用

页码：690 / 694

页数：5

共 50 条

[21] Application of real-time confocal laser scanning microscopy to observe living cells in tissue specimens [J].

Saino, T ;

Satoh, Y .

JOURNAL OF ELECTRON MICROSCOPY, 2004, 53 (01) :49-56

[22] Confocal laser endomicroscopy in the "in vivo" histological diagnosis of the gastrointestinal tract [J].

De Palma, Giovanni D. .

WORLD JOURNAL OF GASTROENTEROLOGY, 2009, 15 (46) :5770-5775

[23] Confocal laser endomicroscopy in the “in vivo” histological diagnosis of the gastrointestinal tract [J].

Giovanni D De Palma .

World Journal of Gastroenterology, 2009, 15 (46) :5770-5775

[24] Examination of the human cornea with the confocal microscope after excimer-laser photorefractive keratectomy [J].

Bohnke, M ;

Schipper, I ;

Thaer, A .

KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE, 1997, 211 (03) :159-167

[25] In vivo real-time imaging of the liver with confocal endomicroscopy permits visualization of the temporospatial patterns of hepatocyte apoptosis [J].

Goetz, Martin ;

Ansems, Jacqueline V. ;

Galle, Peter R. ;

Schuchmann, Marcus ;

Kiesslich, Ralf .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2011, 301 (05) :G764-G772

[26] A three dimensional real-time MEMS based optical biopsy system for in-vivo clinical imaging [J].

McCormick, Daniel T. ;

Jung, Woonggyu ;

Ahn, Yeh-Chan ;

Chen, Zhongping ;

Tien, Norman C. .

TRANSDUCERS '07 & EUROSENSORS XXI, DIGEST OF TECHNICAL PAPERS, VOLS 1 AND 2, 2007,

[27] In vivo confocal laser scanning microscopy in the diagnosis of melanocytic skin tumours [J].

Gerger, A. ;

Hofmann-Wellenhof, R. ;

Samonigg, H. ;

Smolle, J. .

BRITISH JOURNAL OF DERMATOLOGY, 2009, 160 (03) :475-481

[28] Transplantation into the Anterior Chamber of the Eye for Longitudinal, Non-invasive In vivo Imaging with Single-cell Resolution in Real-time [J].

Abdulreda, Midhat H. ;

Caicedo, Alejandro ;

Berggren, Per-Olof .

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2013, (73)

[29] Real-time 3-D underwater imaging and mapping using a laser line scan technique [J].

Caimi, FM ;

Kocak, DM .

OPTICAL SCANNING SYSTEMS: DESIGN AND APPLICATIONS, 1997, 3131 :241-252

[30] Optical endomicroscopy and the road to real-time, in vivo pathology: present and future [J].

Charles S Carignan ;

Yukako Yagi .

Diagnostic Pathology, 7

← 1 2 3 4 5 →