HISTOLOGICAL STUDY OF ALCOHOLIC, NONALCOHOLIC, AND OBSTRUCTIVE CHRONIC-PANCREATITIS

被引：41

作者：

DEANGELIS, C ^{[1
]}

VALENTE, G ^{[1
]}

SPACCAPIETRA, M ^{[1
]}

ANGONESE, C ^{[1
]}

DELFAVERO, G ^{[1
]}

NACCARATO, R ^{[1
]}

ANDRIULLI, A ^{[1
]}

机构：

[1] OSPED SAN GIOVANNI BATTISTA TORINO,DIV GASTROENTEROL,TURIN,ITALY

来源：

PANCREAS | 1992年 / 7卷 / 02期

关键词：

ALCOHOLIC CHRONIC PANCREATITIS; NONALCOHOLIC IDIOPATHIC CHRONIC PANCREATITIS; OBSTRUCTIVE CHRONIC PANCREATITIS;

D O I：

10.1097/00006676-199203000-00010

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Pancreatic tissue obtained from 26 patients with alcoholic chronic pancreatitis (ACP), nine patients with nonalcoholic idiopathic chronic pancreatitis (NAICP), and seven patients with obstructive chronic pancreatitis (OCP) was studied in an attempt to determine whether clinical or etiologic differences have a morphologic counterpart. Histologically it was easy to distinguish ACP from OCP occurring distal to an obstruction of the pancreatic duct. Nine patients with NAICP showed histological features similar to those found in ACP. Plugs and calcifications were found as frequently in NAICP as in ACP, suggesting that NAICP, whatever the etiology, is truly pancreatolithiasis, which leads to slowly progressive fibrosis and acinar atrophy in the obstructed pancreatic lobule. Nerve fibers were found to be more numerous in all disease categories. Inflammatory foci of lymphocytes associated with nerves were observed in 57 and 35% of cases with OCP and ACP, respectively, but only in one patient with NAICP. These findings may constitute a pathological basis for the existing clinical data showing that NAICP frequently runs a pain-free course.

引用

页码：193 / 196

页数：4

共 14 条

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