MIXED ACETOXY-BENZOXY TAXANE ESTERS FROM TAXUS-BREVIFOLIA

被引：25

作者：

CHU, A

ZAJICEK, J

DAVIN, LB

LEWIS, NG

CROTEAU, RB

机构：

[1] WASHINGTON STATE UNIV,INST BIOL CHEM,467 CLARK HALL,PULLMAN,WA 99163

[2] WASHINGTON STATE UNIV,CTR NMR SPECT,PULLMAN,WA 99163

来源：

PHYTOCHEMISTRY | 1992年 / 31卷 / 12期

基金：

美国国家卫生研究院;

关键词：

TAXUS-BREVIFOLIA; TAXACEAE; YEW; BARK; DITERPENOIDS; TAXOL; TAXANES; BACCATIN-VL;

D O I：

10.1016/0031-9422(92)80453-L

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three new taxane derivatives were isolated from the bark of Taxus brevifolia and their structures established as 5beta,20-epoxy-1beta-hydroxy-4alpha-7beta,13alpha-triacetoxy-2alpha,9alpha,10beta-tribenzoxy-tax-11-ene, 2alpha,10beta-dibenzoxy-5beta,20-epoxy-1beta-hydroxy-4alpha,7beta,9alpha,13alpha-tetraacetoxy-tax-11-ene and 2alpha,7beta-dibenzoxy-5beta,20-epoxy-1beta-hydroxy-4alpha,9alpha,10beta,13alpha-tetraacetoxy-tax-11-ene.

引用

页码：4249 / 4252

页数：4

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