ACYCLOGUANOSINE - ANTI-VIRAL ACTIVITY IN THE RABBIT CORNEA

被引：24

作者：

FALCON, MG

JONES, BR

机构：

[1] Department of Clinical Ophthalmology, Institute of Ophthalmology, University of London

[2] Department of Clinical Ophthalmology, Moorfields Eye Hospital, London EC1V 2PD, City Road

来源：

BRITISH JOURNAL OF OPHTHALMOLOGY | 1979年 / 63卷 / 06期

关键词：

D O I：

10.1136/bjo.63.6.422

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

We describe experiments, using the multiple microinoculation technique, to produce superficial herpes simplex keratitis in the rabbit cornea, which showed a potent antiviral effect of acycloguanosine.

引用

页码：422 / 424

页数：3

共 8 条

[1] TREATMENT OF EXPERIMENTAL HERPES-SIMPLEX KERATITIS WITH ACYCLOGUANOSINE [J].

BAUER, DJ ;

COLLINS, P ;

TUCKER, WE ;

MACKLIN, AW .

BRITISH JOURNAL OF OPHTHALMOLOGY, 1979, 63 (06) :429-435

[2] SELECTIVITY OF ACTION OF AN ANTI-HERPETIC AGENT, 9-(2-HYDROXYETHOXYMETHYL)GUANINE [J].

ELION, GB ;

FURMAN, PA ;

FYFE, JA ;

DEMIRANDA, P ;

BEAUCHAMP, L ;

SCHAEFFER, HJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1977, 74 (12) :5716-5720

[3] HERPES-SIMPLEX KERATITIS - ANIMAL-MODELS TO GUIDE SELECTION AND OPTIMAL DELIVERY OF ANTIVIRAL CHEMOTHERAPY [J].

FALCON, MG ;

JONES, BR .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1977, 3 :83-&

[4]

FALCON MG, 1977, T OPHTHAL SOC UK, V97, P330

[5]

JONES B R, 1963, Trans Ophthalmol Soc U K, V83, P613

[6]

JONES BR, 1979, LANCET, V1, P243

[7] 9-(2-HYDROXYETHOXYMETHYL)GUANINE ACTIVITY AGAINST VIRUSES OF HERPES GROUP [J].

SCHAEFFER, HJ ;

BEAUCHAMP, L ;

MIRANDA, PD ;

ELION, GB ;

BAUER, DJ ;

COLLINS, P .

NATURE, 1978, 272 (5654) :583-585

[8]

TUCKER WE, 1978, 18TH INT C ANT AG CH

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