ANTI-ENDO-TOXIN ACTIVITY OF TAUROLIN IN EXPERIMENTAL-ANIMALS

被引：40

作者：

PFIRRMANN, RW

LESLIE, GB

机构：

[1] Research Laboratories, Ed Geistlich Sons Limited, Pharmaceutical Division, Wolhusen, Canton Lucerne

来源：

JOURNAL OF APPLIED BACTERIOLOGY | 1979年 / 46卷 / 01期

关键词：

D O I：

10.1111/j.1365-2672.1979.tb02586.x

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Taurolin, a broad spectrum bactericidal agent, protected experimental animals [mice and rabbits] from the lethal effects of Escherichia coli and Bacteroides fragilis endotoxin. Taurolin also prevented the pyrexic response of rabbits to TAB vaccine. Taurolin possibly exerts its antiendotoxic effect by direct reaction with the endotoxin molecule.

引用

页码：97 / 102

页数：6

共 9 条

[1] BROWNE MK, 1977, SURG GYNECOL OBSTET, V145, P842
[2] BROWNE MK, 1978, SURG GYNECOL OBSTET, V146, P721
[3] TAUROLIN, A NEW CHEMOTHERAPEUTIC AGENT
BROWNE, MK
LESLIE, GB
PFIRRMANN, RW
[J]. JOURNAL OF APPLIED BACTERIOLOGY, 1976, 41 (03): : 363 - 368
[4] BUHLER HU, 1978, HELV CHIR ACTA, V45, P143
[5] GAY B, 1976, CHIRURG, V47, P326
[6] EFFECT OF VARIOUS AMINE-DEPLETING DRUGS ON FEVER RESPONSE EXHIBITED BY RABBITS TO BACTERIAL OR LEUKOCYTE PYROGEN
METCALF, G
THOMPSON, JW
[J]. BRITISH JOURNAL OF PHARMACOLOGY, 1975, 53 (01) : 21 - 27
[7] MOSER G, 1978, SCHWEIZ RUNDSCH MED, V67, P425
[8] URBASCHEK B, 1976, ZBL BAKT-INT J MED M, V235, P26
[9] URBASCHEK B, 1977, MICROBIOLOGY 1977, P286

← 1 →