SPIRANS .15. SPIRANS DERIVED FROM 3-TRIFLUOROMETHYLCYCLOHEXANONE

被引：10

作者：

RICE, LM

SHETH, BS

SCOTT, KR

GESCHICKTER, CF

机构：

[1] Howard University, College of Pharmacy, Washington

[2] Gorgelown University, Medical Center, Washington, D.C.

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1969年 / 12卷 / 01期

关键词：

D O I：

10.1021/jm00301a032

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Various spiro[5.4]decane and spiro[5.5]undecane compounds containing a trifluoromelhyl substitution in the 7 or 8 position have been synthesized. When evaluated biologically, N-(3-dimethyIaminopropyl)-8-trifluoromethyl-3-azaspira [5.5] undecane showed the best activity and is potentially an interesting auticaneer compound. © 1969, American Chemical Society. All rights reserved.

引用

页码：126 / +

页数：1

共 8 条

[1] SIMPLE PROCEDURE FOR CHROMIC ACID OXIDATION OFALCOHOLS TO KETONES OF HIGH PURITY [J].