APPLICATION OF DUAL PARAMETER ANALYSIS IN FLOW CYTOMETRIC DNA MEASUREMENTS OF PARAFFIN-EMBEDDED SAMPLES

被引：7
作者：
NYLANDER, K
STENLING, R
GUSTAFSSON, H
ROOS, G
机构：
[1] UMEA UNIV,DEPT ORAL PATHOL,S-90187 UMEA,SWEDEN
[2] UMEA UNIV,DEPT PATHOL,S-90187 UMEA,SWEDEN
[3] UMEA UNIV,DEPT OTORHINOLARYNGOL,S-90187 UMEA,SWEDEN
来源：
JOURNAL OF ORAL PATHOLOGY & MEDICINE | 1994年 / 23卷 / 04期
关键词：
CYTOKERATIN; DNA CONTENT; FLOW CYTOMETRY; HEAD AND NECK; SQUAMOUS CELL CARCINOMA;
D O I：
10.1111/j.1600-0714.1994.tb01111.x
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
In a comparison of flow cytometric DNA measurements on fresh and paraffin-embedded material from primary squamous cell carcinomas of the head and neck region, we discovered that previously undetected aneuploid clones could be detected by dual parameter analysis of cytokeratin and DNA applied to disintegrated cells from paraffin sections. Using this new approach the correlation coefficient between DNA-indices from fresh and paraffin-embedded material increased from 0.423 to 0.904.
引用
收藏
页码：190 / 192
页数：3
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