SENSITIVITY IMPROVEMENT IN ISOTROPIC MIXING (TOCSY) EXPERIMENTS

被引：161

作者：

CAVANAGH, J

RANCE, M

机构：

[1] Department ofMolecular Biology, Research Institute, Scripps Clinic, La Jolla, CA 92037

来源：

JOURNAL OF MAGNETIC RESONANCE | 1990年 / 88卷 / 01期

关键词：

D O I：

10.1016/0022-2364(90)90109-M

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple modification of the two-dimensional TOCSY experiment which leads to a √2 improvement in sensitivity is described. This improvement is achieved by retaining the magnetization transfer pathways from both of the orthogonal, in-phase magnetization components which are present during the isotropic mixing period. In addition, a simple baseline correction procedure which can greatly improve the quality of NMR spectra is described. © 1990.

引用

页码：72 / 85

页数：14

共 31 条

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