FELINE LEUKEMIA VIRUS - OCCURRENCE OF VIRAL ANTIGEN IN TISSUES OF CATS WITH LYMPHOSARCOMA AND OTHER DISEASES

被引：145

作者：

HARDY, WD

GEERING, G

OLD, LJ

DEHARVEN, E

BRODEY, RS

MCDONOUGH, S

机构：

[1] Sloan-Kettering Institute for Cancer Research, New York

[2] School of Veterinary Medicine, University of Pennsylvania, Philadelphia

来源：

SCIENCE | 1969年 / 166卷 / 3908期

关键词：

D O I：

10.1126/science.166.3908.1019

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Feline leukemia virus antigen is demonstrable by immunodiffusion with rabbit precipitating antiserum to purified feline leukemia virus. The feline leukemia virus antigen was found in the tissues of 25 of 33 cats with lymphosarcoma and of 5 of 13 cats with infectious peritonitis. Its presence was correlated with the occurrence of feline leukemia virus demonstrable by electron microscopy. The one clinically normal cat giving a positive test for feline leukemia virus antigen belonged to a household in which two cats had developed lymphosarcoma. With the exception of a dog with lymphosarcoma induced by feline leukemia virus, the antigen was absent from lymphosarcoma and nonlymphomatous tumors of other species (man, dog, cow, goat, or pig).

引用

页码：1019 / +

页数：1

共 31 条

[1]

AOKI T, 1968, J NATL CANCER I, V41, P97

[2] MULTIPLE GROUP-SPECIFIC ANTIGEN COMPONENTS OF AVIAN TUMOR VIRUSES DETECTED WITH CHICKEN AND HAMSTER SERA [J].