ADAPTABLE HEXOKINASE WITH LOW-AFFINITY FOR GLUCOSE IN THE LIVER OF ATLANTIC SALMON (SALMO-SALAR)

1. The results show the presence of an adaptable hexokinase (glucokinase) with low affinity for glucose in salmon liver. The activity of this enzyme increased gradually when dietary starch was increased from 0 to 30% at the expense of dietary protein. 2. The change in dietary carbohydrate/protein had minor, but statistically significant effects on hepatic glucose dehydrogenase (EC 1.1.1.47), glucose-6-phosphate dehydrogenase (EC 1.1.1.49), malic enzyme (NADP malate dehydrogenase, EC 1.1.1.40), citrate lyase (EC 4.1.3.6), and fructose-1,6-bisphosphatase (EC 3.1.3.11). 3. The activity of glucose-6-phosphate dehydrogenase was maximal after feeding 10% dietary starch which also was the optimal amount as judged from energetic factors.