Role of Hybrid Brain Imaging in Neuropsychiatric Disorders

被引：8

作者：

Burhan, Amer M. ^{[1
,2
]}

Marlatt, Nicole M. ^{[1
]}

Palaniyappan, Lena ^{[2
]}

Anazodo, Udunna C. ^{[3
]}

Prato, Frank S. ^{[3
]}

机构：

[1] St Josephs Hlth Care London, Parkwood Inst, 550 Wellington Rd, London, ON N6C 0A7, Canada

[2] Univ Western Ontario, Schulich Sch Med & Dent, Dept Psychiat, London, ON N6C 2R6, Canada

[3] Lawson Hlth Res Inst, London, ON N6C 2R5, Canada

来源：

DIAGNOSTICS | 2015年 / 5卷 / 04期

关键词：

neuropsychiatric disorders; neuroimaging; humans; brain disorders/diagnosis; hybrid imaging; molecular imaging; neuronal networks; Alzheimer's disease; schizophrenia; affective disorders;

D O I：

10.3390/diagnostics5040577

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This is a focused review of imaging literature to scope the utility of hybrid brain imaging in neuropsychiatric disorders. The review focuses on brain imaging modalities that utilize hybrid (fusion) techniques to characterize abnormal brain molecular signals in combination with structural and functional changes that have been observed in neuropsychiatric disorders. An overview of clinical hybrid brain imaging technologies for human use is followed by a selective review of the literature that conceptualizes the use of these technologies in understanding basic mechanisms of major neuropsychiatric disorders and their therapeutics. Neuronal network abnormalities are highlighted throughout this review to scope the utility of hybrid imaging as a potential biomarker for each disorder.

引用

页码：577 / 614

页数：38

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