DIFFERENCES IN THE AC ELECTRODYNAMICS OF VIABLE AND NONVIABLE YEAST-CELLS DETERMINED THROUGH COMBINED DIELECTROPHORESIS AND ELECTROROTATION STUDIES

被引:369
作者
YING, H
HOLZEL, R
PETHIG, R
WANG, XB
机构
[1] Inst. of Mole. and Biomole. Electron., Wales Univ., Bangor
关键词
D O I
10.1088/0031-9155/37/7/003
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
An electrode system is described for the near-simultaneous application and measurement of translational, levitational and rotational forces induced by AC electric fields, and this has been used to investigate the differences in the Ac electrodynamics of viable and non-viable yeast cells. A new approach to the theoretical modelling of the experimental data has enabled these differences to be quantified in terms of changes in the conductivity of the cytoplasmic membrane and cell interior. The results are considered to have potentially important biomedical and biotechnological applications.
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页码:1499 / 1517
页数:19
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