EFFECT OF PROPRANOLOL ON VENTRICULAR ARRHYTHMIAS INDUCED BY HYPERCARBIA DURING HALOTHANE ANAESTHESIA IN MAN

被引：9
作者：
FUKUSHIMA, K
FUJITA, T
FUJIWARA, T
OOSHIMA, H
SATO, T
机构：
来源：
BRITISH JOURNAL OF ANAESTHESIA | 1968年 / 40卷 / 01期
关键词：
D O I：
10.1093/bja/40.1.53
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
Summary: The effects of propranolol on arterial blood pressure, heart rate, and cardiac rhythm during ventricular arrhythmias initiated by hypercarbia were investigated in thirteen subjects during 1 per cent halothane anaesthesia. Propranolol was consistently effective in the treatment of ventricular arrhythmia induced by hypercarbia in all subjects. The successful use of propranolol suggests that the mechanism for ventricular arrhythmia produced by respiratory acidosis during halothane anaesthesia was related to beta adrenergic receptors. Blockade of these receptors by beta adrenergic agents decreased markedly the sensitization of myocardium to sympathetic stimulation. © 1968 John Sherratt and Son Ltd.
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页码：53 / +
页数：1
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