BIPOLAR AFFECTIVE-DISORDERS LINKED TO DNA MARKERS ON CHROMOSOME-11

被引：677
作者：
EGELAND, JA
GERHARD, DS
PAULS, DL
SUSSEX, JN
KIDD, KK
ALLEN, CR
HOSTETTER, AM
HOUSMAN, DE
机构：
[1] MIT, DEPT BIOL, CAMBRIDGE, MA 02139 USA
[2] YALE UNIV, SCH MED, CTR CHILD STUDY, NEW HAVEN, CT 06510 USA
[3] YALE UNIV, SCH MED, DEPT HUMAN GENET, NEW HAVEN, CT 06510 USA
[4] YALE UNIV, SCH MED, DEPT PSYCHIAT, NEW HAVEN, CT 06510 USA
来源：
NATURE | 1987年 / 325卷 / 6107期
关键词：
D O I：
10.1038/325783a0
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
An analysis of the segregation of restriction fragment length polymorphisms in an Old Order Amish pedigree has made it possible to localize a dominant gene conferring a strong predisposition to manic depressive disease to the tip of the short arm of chromosome 11.
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页码：783 / 787
页数：5
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