INHIBITION OF GLUTATHIONE SYNTHESIS AS A CHEMOTHERAPEUTIC STRATEGY FOR TRYPANOSOMIASIS

被引：127

作者：

ARRICK, BA ^{[1
]}

GRIFFITH, OW ^{[1
]}

CERAMI, A ^{[1
]}

机构：

[1] CORNELL UNIV,COLL MED,DEPT BIOCHEM,NEW YORK,NY 10021

来源：

JOURNAL OF EXPERIMENTAL MEDICINE | 1981年 / 153卷 / 03期

关键词：

D O I：

10.1084/jem.153.3.720

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：720 / 725

页数：6

共 19 条

[1] DEFICIENT METABOLIC UTILIZATION OF HYDROGEN-PEROXIDE IN TRYPANOSOMA-CRUZI [J].

BOVERIS, A ;

SIES, H ;

MARTINO, EE ;

DOCAMPO, R ;

TURRENS, JF ;

STOPPANI, OM .

BIOCHEMICAL JOURNAL, 1980, 188 (03) :643-648

[2]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[3] HYDROPEROXIDE METABOLISM IN MAMMALIAN ORGANS [J].

CHANCE, B ;

SIES, H ;

BOVERIS, A .

PHYSIOLOGICAL REVIEWS, 1979, 59 (03) :527-605

[4]

CHANG KP, 1975, P NATL ACAD SCI US, V71, P2979

[5] LOCALIZATION OF PEROXIDASE-ACTIVITY IN TRYPANOSOMA-CRUZI MICROBODIES [J].

DOCAMPO, R ;

DEBOISO, JF ;

BOVERIS, A ;

STOPPANI, AOM .

EXPERIENTIA, 1976, 32 (08) :972-975

[6]

DUGGAN AJ, 1970, AFRICAN TRYPANOSOMIA

[7] INHIBITION OF THE RESPIRATION OF TRYPANOSOMA-RHODESIENSE BY THIOLS [J].

FULTON, JD ;

SPOONER, DF .

BIOCHEMICAL JOURNAL, 1956, 63 (03) :475-481

[8] GLUTATHIONE - INTERORGAN TRANSLOCATION, TURNOVER, AND METABOLISM [J].

GRIFFITH, OW ;

MEISTER, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1979, 76 (11) :5606-5610

[9]

GRIFFITH OW, 1979, J BIOL CHEM, V254, P7558

[10] NONSPECIFIC REACTIONS OF GLUTATHIONE OXIDANT DIAMIDE WITH MAMMALIAN-CELLS [J].

HARRIS, JW ;

BIAGLOW, JE .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1972, 46 (05) :1743-&

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