Plasticity in neural crest cell differentiation

被引:46
|
作者
Le Douarin, Nicole M. [1 ]
Ziller, Catherine
机构
[1] CNRS, Inst Embryol Cellulaire & Mol, F-94736 Nogent Sur Marne, France
关键词
abrAM-adrenomedullary; AP-anteroposterior; BDNF-brain-derived neurotrophic factor; CA-catecholamines; CEE-chick embryo extract; CNS-central nervous system; DRG-dorsal root ganglia; E-embryonic day; ECM-extracellular matrix; ENS-enteric nervous system; GFAP-filial fibrillary acidic protein; HLH-helix-loop-helix; LIF-leukemia inhibitor factor; LN-laminin; MAG-myelin-associated glycoprotein; MASH-mammalian achaete-scute homologue; PNS-peripheral nervous system; SA-sympatho-adrenal; SG-sympathetic ganglia; SMP-Schwann cell myelin protein; TH-tyrosine hydroxylase; TPA-12-O-tetradecanoyl phorbol-13-acetate;
D O I
10.1016/0955-0674(93)90089-9
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The neural crest is a pluripotent population of cells that are endowed with migratory capacities. It has long been known that the differentiation pathway taken by cells derived from the neural crest is largely controlled by the microenvironment to which they home after their migration phase, indicating a high degree of plasticity in their developmental fate. Recent progress has been made concerning the factors which influence survival, growth and differentiation of selected sets of precursors in each embryonic site colonised by derivatives of the neural crest
引用
收藏
页码:1036 / 1043
页数:8
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