Incidental Squamous Cell Carcinoma in an Epidermal Inclusion Cyst: A Case Report and Review of the Literature

被引:27
作者
Frank, Ethan [1 ]
Macias, David [1 ]
Hondorp, Brian [2 ]
Kerstetter, Justin [3 ]
Inman, Jared C. [2 ]
机构
[1] Loma Linda Univ, Sch Med, Loma Linda, CA USA
[2] Loma Linda Univ, Dept Otolaryngol Head & Neck Surg, Loma Linda, CA 92350 USA
[3] Loma Linda Univ, Dept Pathol & Lab Med, Loma Linda, CA 92350 USA
关键词
Epidermal cyst; Inclusion cyst; Cutaneous cyst; Squamous cell carcinoma; Malignant transformation;
D O I
10.1159/000487794
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Epidermal inclusion cysts are common lesions that rarely develop into squamous cell carcinoma (SCC). Neoplastic change in these cysts can be associated with prominent symptoms such as pain, rapid growth, or ulceration. This study describes the case of a 64-year-old woman with a 4-year history of a largely asymptomatic neck mass, which after routine excision was found to be an epidermal inclusion cyst harboring well-differentiated SCC. The diagnosis was made incidentally after routine cyst bisection and hematoxylin and eosin staining. Given the potential for variable presentation and low cost of hematoxylin and eosin analysis, we recommend a low threshold for a comprehensive pathological search for malignancy in excised cysts when appropriate. (c) 2018 The Author(s) Published by S. Karger AG, Basel
引用
收藏
页码:61 / 68
页数:8
相关论文
共 13 条
[1]  
Kshirsagar Ashok Y, 2011, J Cutan Aesthet Surg, V4, P48, DOI 10.4103/0974-2077.79195
[2]   Squamous Cell Carcinoma Arising from an Epidermal Inclusion Cyst [J].
Lee, Jin-Won ;
Shin, Jin-Yong ;
Roh, Si-Gyun ;
Lee, Nae-Ho ;
Yang, Kyung-Moo .
ARCHIVES OF PLASTIC SURGERY-APS, 2016, 43 (01) :112-+
[3]   Orbital Invasion by Squamous Cell Carcinoma Arising in Multiple Epidermoid Cysts [J].
Milbratz, Gherusa Helena ;
Borges, Felipe Placeres ;
Cintra, Murilo Bicudo ;
Barros Silva, Gyl Eanes ;
Velasco e Cruz, Antonio Augusto .
OPHTHALMIC PLASTIC AND RECONSTRUCTIVE SURGERY, 2012, 28 (06) :E144-E144
[4]  
Mohan C, 2016, INT J ADV INTEGR MED, V1, P15
[5]   Squamous cell carcinoma arising in epidermoid cysts: Report of four cases and review of the literature [J].
Morritt, A. N. ;
Tiffin, N. ;
Brotherston, T. M. .
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, 2012, 65 (09) :1267-1269
[6]  
Pusiol T, 2010, PATHOLOGICA, V102, P88
[7]   Squamous cell carcinoma arising from an epidermal cyst in the thumb [J].
Sakamoto, Akio ;
Shiba, Eisuke ;
Hisaoka, Masanori .
INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 2015, 11 :37-39
[8]   Squamous Cell Carcinoma Developing from an Epidermoid Cyst of the Ear [J].
Shabbir, Arsalan ;
Loss, Lesley ;
Bogner, Paul ;
Zeitouni, Nathalie C. .
DERMATOLOGIC SURGERY, 2011, 37 (05) :700-703
[9]   Isotretinoin for the treatment of squamous cell carcinoma arising on an epidermoid cyst [J].
Skroza, Nevena ;
Proietti, Ilaria ;
Tolino, Ersilia ;
Bernardini, Nicoletta ;
La Viola, Giorgio ;
Nicolucci, Francesca ;
Pampena, Riccardo ;
Mancini, Maria Teresa ;
Balduzzi, Veronica ;
Potenza, Concetta .
DERMATOLOGIC THERAPY, 2014, 27 (02) :94-96
[10]   Squamous cell carcinoma arising in an epidermal cyst [J].
Sridevi, H. B. ;
Shariff, M. H. ;
Pai, Pushpalatha K. .
INDIAN JOURNAL OF CANCER, 2015, 52 (03) :335-336