DYNAMICS OF GLUTATHIONE IN AQUEOUS-SOLUTION

It would play an important role in understanding molecular active functions to study bimolecular intermotion. C-13 longitudinal relaxation which could reflect information of molecular or intermolecular motion provides a very powerful technique for the study of molecular motion. In this note, the C-13 longitudinal relaxation time (T-1) and NOE values of oxidized and reduced glutathione (GSSG and GSH) have been measured under the conditions of different temperatures and magnetic fields. The various relaxation mechanisms were separated, and rotational active energies of carbons were calculated. It is studied for the first time that the kinetic parameters of GSH change correspondingly with concentration of Fe3+ ions in solution. Significant results and conclusion about interaction between small polypeptide and trace metal cations have been obtained.