EVALUATION OF RETINOIDS AS THERAPEUTIC AGENTS IN DERMATOLOGY

被引：17

作者：

LEWIN, AH ^{[1
]}

BOS, ME ^{[1
]}

ZUSI, FC ^{[1
]}

NAIR, X ^{[1
]}

WHITING, G ^{[1
]}

BOUQUIN, P ^{[1
]}

TETRAULT, G ^{[1
]}

CARROLL, FI ^{[1
]}

机构：

[1] BRISTOL MYERS SQUIBB CO,DIV PHARMACEUT RES & DEV,DERMATOL RES,BUFFALO,NY 14213

来源：

PHARMACEUTICAL RESEARCH | 1994年 / 11卷 / 02期

关键词：

RETINOIDS; ANTIHYPERKERATINIZATION; ANTIHYPERPROLIFERATION; ANTIHYPERACTIVE SEBACIOUS GLAND; HYPERVITAMINOSIS A;

D O I：

10.1023/A:1018938920796

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Evaluation of 13-cis-12-substituted analogues of retinoic acid in a series of dermatologic screens has revealed that structural modifications can lead to selectivity and specificity. An analogue, 11-cis,13-cis-12-hydroxymethylretinoic acid, delta-lactone, has been found to have good activity and to be devoid of topical and systemic toxicity.

引用

页码：192 / 200

页数：9

共 50 条

[41] THE DEVELOPMENT OF RETINOIDS IN EXPERIMENTAL AND CLINICAL ONCOLOGY AND DERMATOLOGY
BOLLAG, W
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1983, 9 (05) : 797 - 805
[42] EVALUATION OF THERAPEUTIC AGENTS AND COSMETICS
HAALAND, EM
POSTGRADUATE MEDICINE, 1965, 37 (02) : A210 - &
[43] Injectable and topical neurotoxins in dermatology Basic science, anatomy, and therapeutic agents
Giordano, Cerrene N.
Matarasso, Seth L.
Ozog, David M.
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2017, 76 (06) : 1013 - 1026
[44] Ciclopirox and Ciclopirox Olamine: Antifungal Agents in Dermatology with Expanding Therapeutic Potential
Mucha, Paulina
Borkowski, Bartlomiej
Erkiert-Polguj, Anna
Budzisz, Elzbieta
APPLIED SCIENCES-BASEL, 2024, 14 (24):
[45] EVALUATION OF TOPICAL DICHLOROXYQUINALDINE (STEROSAN) AS A THERAPEUTIC AGENT IN DERMATOLOGY
TRONSTEIN, AJ
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1949, 13 (03) : 119 - 123
[46] ROLE OF FAT-STORING CELLS IN HEPATIC FIBROGENESIS - RETINOIDS AS POSSIBLE THERAPEUTIC AGENTS
DEBLESER, P
GEERTS, A
WISSE, E
ALCOHOL AND ALCOHOLISM, 1991, : 345 - 350
[47] PROBLEMATIC ASPECTS IN EVALUATION OF TERATOGENIC AGENTS AS THERAPEUTIC AGENTS
GROSDANOFF, P
WIENER KLINISCHE WOCHENSCHRIFT, 1977, 89 (15) : 536 - 537
[48] Current Use and Future Potential Role of Retinoids in Dermatology
Constantin E. Orfanos
Christos C. Zouboulis
Brigitte Almond-Roesler
Christoph C. Geilen
Drugs, 1997, 53 : 358 - 388
[49] AROTINOIDS - A NEW CLASS OF RETINOIDS WITH ACTIVITIES IN ONCOLOGY AND DERMATOLOGY
BOLLAG, W
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1981, 7 (01) : 27 - 29
[50] Current use and future potential role of retinoids in dermatology
Orfanos, CE
Zouboulis, CC
AlmondRoesler, B
Geilen, CC
DRUGS, 1997, 53 (03) : 358 - 388

← 1 2 3 4 5 →