FORMULATION OF ORAL MUCOSAL DRUG-DELIVERY SYSTEMS FOR THE SYSTEMIC DELIVERY OF BIOACTIVE MATERIALS

被引:15
|
作者
PONCHEL, G
机构
[1] Laboratoire de Pharmacotechnie et de Biopharmacie, URA CNRS 1218, Faculté de Pharmacie, Châtenay-Malabry
关键词
BUCCAL DRUG DELIVERY; BIOADHESION; POLYMERS; TABLETS; PATCHES; DRUG DELIVERY DEVICES; FORMULATION;
D O I
10.1016/0169-409X(94)90027-2
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
The bioavailability of drugs delivered via the oral route can be influenced byseveral factors, including formulation factors. In this paper the conceptual and technical approaches to the design and formulation of oral mucosal drug delivery systems are reviewed, and the major problems encountered in the design of efficient oral mucosal drug delivery systems are highlighted.
引用
收藏
页码:75 / 87
页数:13
相关论文
共 50 条
  • [1] Drug-Delivery Systems for Tunable and Localized Drug Release
    Timko, Brian P.
    Kohane, Daniel S.
    ISRAEL JOURNAL OF CHEMISTRY, 2013, 53 (9-10) : 728 - 736
  • [2] Polymers in Mucoadhesive Drug-Delivery Systems: A Brief Note
    Roy, S.
    Pal, K.
    Anis, A.
    Pramanik, K.
    Prabhakar, B.
    DESIGNED MONOMERS AND POLYMERS, 2009, 12 (06) : 483 - 495
  • [3] BIOADHESIVE DRUG DELIVERY SYSTEMS FOR ORAL APPLICATION
    LEHR, CM
    PHARMACEUTISCH WEEKBLAD-SCIENTIFIC EDITION, 1992, 14 (03) : 95 - 96
  • [4] Development and Characterization of Self-nano-emulsifying Drug-delivery System for Oral Delivery of Verapamil
    Kola, Venu
    Jadhav, Nilesh
    Chavan, Anuradha
    Panga, Shyam
    ASIAN JOURNAL OF PHARMACEUTICS, 2022, 16 (04) : 508 - 516
  • [5] An investigation of bioadhesion for periodontal and oral mucosal drug delivery
    Needleman, IG
    Smales, FC
    Martin, GP
    JOURNAL OF CLINICAL PERIODONTOLOGY, 1997, 24 (06) : 394 - 400
  • [6] Nanotechnology-based mucoadhesive and mucus-penetrating drug-delivery systems for transbuccal drug delivery
    Desai, Digvijay Dattatray
    Manikkath, Jyothsna
    Lad, Hitesh
    Kulkarni, Mugdha
    Manikkath, Aparna
    Radhakrishnan, Raghu
    NANOMEDICINE, 2023, 18 (21) : 1495 - 1514
  • [7] Stabilization Challenges and Formulation Strategies Associated with Oral Biologic Drug Delivery Systems
    Truong-Le, Vu
    Lovalenti, Phillip M.
    Abdul-Fattah, Ahmad M.
    ADVANCED DRUG DELIVERY REVIEWS, 2015, 93 : 95 - 108
  • [8] Characterisation of bioadhesives for periodontal and oral mucosal drug delivery
    Needleman, IG
    Martin, GP
    Smales, FC
    JOURNAL OF CLINICAL PERIODONTOLOGY, 1998, 25 (01) : 74 - 82
  • [9] Oral bioadhesive drug delivery systems
    Bruschi, ML
    de Freitas, O
    DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2005, 31 (03) : 293 - 310
  • [10] Polymeric controlled drug-delivery systems: Perspective issues and opportunities
    Kumar, MNVR
    Kumar, N
    DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 2001, 27 (01) : 1 - 30