PREPARATION OF CARBOCYCLIC PHOSPHONATE NUCLEOSIDES

被引：28
|
作者：
JAHNE, G
MULLER, A
KROHA, H
ROSNER, M
HOLZHAUSER, O
MEICHSNER, C
HELSBERG, M
WINKLER, I
RIESS, G
机构：
[1] HOECHST AG, SBU Antiinfectives - Research, 6230 Frankfurt am Main 80, G 838
来源：
TETRAHEDRON LETTERS | 1992年 / 33卷 / 37期
关键词：
D O I：
10.1016/S0040-4039(00)79086-1
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A versatile and high-yielding synthesis of racemic carbocyclic phosphonate nucleosides of adenine, hypoxanthine, guanine, cytosine, uracil, and thymine has been developed. These newly prepared compounds are isosteric (and isoelectronic) with (carbo)cyclic 2,3-dideoxy- and 2,3-dideoxy-2',3'-didehydronucleoside monophosphates.
引用
收藏
页码：5335 / 5338
页数：4
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