ANTIARRHYTHMIC EFFECT OF YOHIMBINE ON ACONITINE-INDUCED CARDIAC-ARRHYTHMIAS IN THE RAT

被引：0

作者：

THOMAS, GP ^{[1
]}

STEPHEN, PM ^{[1
]}

机构：

[1] CHRISTIAN MED COLL & HOSP,DEPT PHARMACOL,VELLORE 632002,INDIA

来源：

ASIA PACIFIC JOURNAL OF PHARMACOLOGY | 1991年 / 6卷 / 03期

关键词：

YOHIMBINE; QUINIDINE; ACONITINE; CARDIAC ARRHYTHMIAS;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Yohimbine was studied for its effect on aconitine induced cardiac arrhythmias in rats. Aconitine was infused intravenously and the time of onset of initial arrhythmias and ventricular tachycardia was noted in yohimbine (1.25, 2.5 and 5.0 mg kg-1) and quinidine (5.0 mg kg-1) treated rats. Yohimbine like the antiarrhythmic agent quinidine, showed significant antiarrhythmic activity, and delayed the onset of the arrhythmic stages produced by aconitine.

引用

页码：259 / 262

页数：4